Fluorescence Correlation Spectroscopy Publications

Below you will find publications of specific FCS applications and several excellent reviews, divided into these categories:

  1. FCS Review Articles
  2. Solution Applications of FCS
  3. Cellular Applications of FCS

FCS Review Articles

(Rigler 1995) Fluorescence correlations, single molecule detection and large number screening. Applications in biotechnology. J Biotechnol. 41:177.

(Schwille 2001) Fluorescence correlation spectroscopy and its potential for intracellular applications. Cell Biochem Biophys. 34(3): 383.

(Hess, Huang et al. 2002) Biological and chemical applications of fluorescence correlation spectroscopy: a review. Biochemistry 41(3): 697.

(Medina and Schwille 2002) Fluorescence correlation spectroscopy for the detection and study of single molecules in biology. Bioessays. 24(8):758.

(Elson 2004) Quick tour of fluorescence correlation spectroscopy from its inception. J Biomed Opt. 9(5):857.

(Thompson, Lieto et al. 2002) Recent advances in fluorescence correlation spectroscopy. Curr Opin Struct Biol. 12(5):634.

(Bulseco and Wolf 2007) Fluorescence correlation spectroscopy: molecular complexing in solution and in living cells. Methods Cell Biol. 81: 525.

(Berland 2004) Fluorescence correlation spectroscopy: a new tool for quantification of molecular interactions. Methods Mol Biol. 261:383.

Solution Applications of FCS

(Frieden, Chattopadhyay et al. 2002) What fluorescence correlation spectroscopy can tell us about unfolded proteins. Adv Protein Chem 62:91.

(Chattopadhyay, Saffarian et al. 2005) Measuring unfolding of proteins in the presence of denaturant using fluorescence correlation spectroscopy. Biophys J. 88(1):1413.

(Foldes-Papp 2006) What it means to measure a single molecule in a solution by fluorescence fluctuation spectroscopy. Exp Mol Pathol. 80(3):209.

(Grunwald, Cardoso et al. 2005) Diffusion and binding properties investigated by Fluorescence Correlation Spectroscopy (FCS). Curr Pharm Biotechnol. 6(5):381.

(Lagerkvist, Foldes-Papp et al. 2001) Fluorescence correlation spectroscopy as a method for assessment of interactions between phage displaying antibodies and soluble antigen. Protein Sci. 10(8):1522.

(Bjorling, Kinjo et al. 1998) Fluorescence correlation spectroscopy of enzymatic DNA polymerization. Biochemistry. 37(37):12971.

(Schwille, Oehlenschlager et al. 1996) Quantitative hybridization kinetics of DNA probes to RNA in solution followed by diffusional fluorescence correlation analysis. Biochemistry. 35(31):10182.

Cellular Applications of FCS

(Widengren and Rigler 1998) Fluorescence correlation spectroscopy as a tool to investigate chemical reactions in solutions and on cell surfaces. Cell Mol Biol (Noisy-le-grand) 44(5):857.

(Lippincott-Schwartz, Snapp et al. 2001) Studying protein dynamics in living cells. Nat Rev Mol Cell Biol 2(6):444.

(Hink, Bisselin et al. 2002) Imaging protein-protein interactions in living cells. Plant Mol Biol. 50(6):871.

(Vukojevic, Pramanik et al. 2005) Study of molecular events in cells by fluorescence correlation spectroscopy. Cell Mol Life Sci 62(5):535.

(Pramanik 2004) Ligand-receptor interactions in live cells by fluorescence correlation spectroscopy. Curr Pharm Biotechnol. 5(2):205.

(Zhong, Pramanik et al. 2001) Insulin binding monitored by fluorescence correlation spectroscopy. Diabetologia. 44(8):1184.

(Sako, Minoghchi et al. 2000) Single-molecule imaging of EGFR signalling on the surface of living cells. Nat Cell Biol. 2(3):168.

(Politz, Browne et al. 1998) Intranuclear diffusion and hybridization state of oligonucleotides measured by fluorescence correlation spectroscopy in living cells. Proceedings National Academy of Sciences. 95:6043.